Cic edizioni internazionali
Clinical Cases and Reviews in Epilepsy

Successful surgical outcome in a patient with coexistence of focal epilepsy due to DNET and Jeavons Syndrome

Brief report/Clinical case, 83 - 86
doi: 10.11138/ccre/2016.1.1.083
Tag this article
Abstract
Enhanced HTML Full text PDF
The coexistence of symptomatic and idiopathic epilepsy has rarely been described and may pose diagnostic and therapeutic challenges. We herein describe a patient with focal epilepsy due to dysembryoblastic neuro-epithelial tumors (DNET) associated with Jeavons Syndrome, who underwent successful lesionectomy. At the age of 13 years, this boy presented rare generalized tonicclonic seizures controlled by valproic acid. Two years later, dyscognitive focal seizures occurred. Eyelid myoclonia with or without absences (EMA) occurring after eye-closure, photoparoxysmal response and focal seizures arising from left temporal lobe were recorded by video-EEG. Brain MRI revealed a left temporal DNET. The combination of different antiepileptic drugs gave no benefit. Due to drug-resistant disabling temporal lobe seizures, patient underwent lesionectomy. At 33-month follow-up, patient was free from temporal lobe seizures. Notably, despite the persistence of EMA, patient’s quality of life greatly improved. This report highlights the importance to consider surgery even in patients with coexistence of both symptomatic and idiopathic epilepsies.e.

Vol. 2 (No. 1) 2017 Janaury - December

  1. Post-stroke seizures: a clinical approach to diagnosis and treatment
    Brigo F., Bragazzi N.L., Nardone R.
    doi: 10.11138/ccre/2017.2.1.001
  2. Psychogenic non-epileptic seizures: an overview on terminology, epidemiology and diagnostic features
    Brigo F., Igwe S.C., Tezzon F., Nardone R.
    doi: 10.11138/ccre/2017.2.1.007
  3. Drug resistant epilepsy in a young male with Cat Eye Syndrome: a case study
    Verri A., Terzaghi M., Maffoni M., Caselli R., Recalcati M.P., Rognone E.
    doi: 10.11138/ccre/2017.2.1.015
  4. Stereotypy of psychogenic nonepileptic seizurelike events compared to temporal lobe seizures: a quantitative analysis of ictal events captured during Video EEG monitoring
    Vogrig A,, Hsiang J.C., Parvizi J.
    doi: 10.11138/ccre/2017.2.1.020
  5. Super-refractory status epilepticus or degenerative encephalopathy with rapid progression? A case report
    Pappalardo I., Cortellazzi P., de Curtis M., Didato G., Pastori C., Minardi I., Beretta S., Michelucci R., Villani F.
    doi: 10.11138/ccre/2017.2.1.027
  6. Polymicrogyria: the bigger the malformation, the worse the epilepsy, is that true?
    Mirandola L., Nobile G., Monti G., Giovannini G., Meletti S.
    doi: 10.11138/ccre/2017.2.1.033
  7. Is genetic aetiology an absolute contraindication for epilepsy surgery? Description of two patients with focal genetic epilepsy who underwent presurgical study
    Ferri L., Bisulli F., Mai R., Lichetta L., Leta C., Nobili L., Muccioli L., Mostacci B., Pippucci T., Tinuper P.
    doi: 10.11138/ccre/2017.2.1.037
  8. First clinical experiences with perampanel in adult patients with drug-resistant epilepsy and cognitive impairment
    Orlando B., Martino T., Quitadamo S.G., Di Claudio M.T., Lalla A., Avolio C., d'Orsi G.
    doi: 10.11138/ccre/2017.2.1.043
  9. Surgical indication and controversies in temporal lobe epilepsy of uncertain lateralisation associated with a unilateral glioneuronal lesion: report of two cases
    Marino D., Tumminelli G., Rocchi R., Bocci S., Pucci B., Sestini S., Cacciola F., Vatti G.
    doi: 10.11138/ccre/2017.2.1.049
  10. Epileptic phenotypes related to the UNC79-UNC80-NALCN protein complex
    Cossu S., Angius A., Oppo M., Onano S., Persico I., Persico I., Uva P., Cuccuru G., Asunis M., Crisponi L., Pruna D.
    doi: 10.11138/ccre/2017.2.1.054
  11. Axial propriospinal myoclonus misdiagnosed as myoclonic seizures
    Pascarella M.G., Martino T., Di Claudio M.T., Avolio C., d'Orsi G.
    doi: 10.11138/ccre/2017.2.1.059
  12. Atypical focal ESES/CSWSS: a clinical case
    Fatuzzo D., Giuliano L., Mainieri G., Lingenti V., Sofia V.
    doi: 10.11138/ccre/2017.2.1.062
  13. A novel de novo SCN8A mutation in an Italian child treated with Levetiracetam: a case in discussion
    Galati C., Isgrò A.R., Lo Re E., Calabrò N., Sgro D.L., Spanò M., Gagliano A.
    doi: 10.11138/ccre/2017.2.1.066
  14. Transauricular Vagus Nerve Stimulation (t-VNS) as a valid predictor of invasive VNS efficacy in drug resistant epilepsy: a case-report
    Barbella G., Freri E., Marotta G., Di Franesco J.C., Ferrarese C., Casazza M
    doi: 10.11138/ccre/2017.2.1.074
  15. Super-refractory status epilepticus in children: what happens when anesthetic therapy is not enough?
    Caputo D., Stoppa F., Vigevano F., Fusco L.
    doi: 10.11138/ccre/2017.2.1.080
  16. Ictal lateralized periodic discharges presenting as epilepsia partialis continua in a patient with chronic stroke
    Colombo M., Beretta S., Bogliun G., Ferrarese C.
    doi: 10.11138/ccre/2017.2.1.088
  17. Fixation-off sensitivity in a girl with symptomatic occipital epilepsy admitted in non-convulsive status epilepticus
    Puentes N.A., Menéndez A.G., Pérez Gil O., García Gutiérrez P.
    doi: 10.11138/ccre/2017.2.1.091
Last Viewed articles: la lista degli ultimi x visitati.
  1. Successful surgical outcome in a patient with coexistence of focal epilepsy due to DNET and Jeavons Syndrome
    Bellavia M.A., Ferlazzo E., Gasparini S., Cianci V., Tripodi G.G., D’Agostino T., Gangemi A., Versace P., Campello M., Aguglia U.
    doi: 10.11138/ccre/2016.1.1.083
credits